Dermatofibrosarcoma Protuberans: Update on the Diagnosis and Treatment

Imatinib in the treatment of dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans (DFSP) is a soft tissue tumor with tendency to recur locally and only rarely metastasizes to vital organs. Surgery with wide margins remains the standard treatment. DFSP is characterized by specific chromosomal abnormalities involving the platelet derived growth factor B locus (PDGFB). In the majority of cases a supernumerary ring chromosome containing amplified ...

Surgical Treatment of Enormous Recurrent Dermatofibrosarcoma Protuberans

A patient with enormous recurrent dermatofibrosarcoma protuberans underwent modified three-dimensional histology surgery. Frozen-section examination was used to identify the margins. The patient had a normal postoperative course.

Dermatofibrosarcoma protuberans.

Overview The NCCN Non-Melanoma Skin Cancer Panel has developed these guidelines outlining the treatment of dermatofibrosarcoma protuberans (DFSP) to supplement their other guidelines (NCCN Clinical Practice Guidelines in Oncology [NCCN Guidelines] for Basal Cell and Squamous Cell Skin Cancers and Merkel Cell Carcinoma; to view the most recent version of these guidelines, visit the NCCN Web site...

Dermatofibrosarcoma Protuberans of The Face:

We report on a patient who presented on the ear, nose and throat (ENT) clinic with swelling on the right temporal region. Imaging studies revealed an expansive process of the skin and subcutaneous tissues of the right preauricular region. Post intravenous contrast administration revealed an ovoid mass with high enhancement without affecting the parotid gland. The patient underwent tumor resecti...

Dermatofibrosarcoma Protuberans in Childhood